The triad interaction of ULK1, ATG13, and FIP200 is required for ULK complex formation and autophagy
In mammals, autophagosome formation, a central event in autophagy, is initiated by the ULK complex comprising ULK1/2, FIP200, ATG13, and ATG101. However, the structural basis and mechanism of the ULK ...
A high density of tumor-associated macrophages (TAMs) is associated with poorer prognosis and survival in breast cancer patients. Recent studies have shown that lipid accumulation in TAMs can promote ...
Propranolol reduces experimental murine cerebral cavernous malformations (CCMs) and prevents embryonic caudal venous plexus (CVP) lesions in zebrafish that follow mosaic inactivation of ccm2. Because ...
This useful study by Gao et al identifies Hspa2 as a heterogeneous transcript in the early embryo and proposes a plausible mechanism showing interactions with Carm1. The authors propose that ...
Researchers have identified a set of geological reaction conditions that may have catalysed life on Earth. Researchers have discovered a plausible evolutionary setting in which nucleic acids – the ...
Changes in neural activity thought to reflect brain aging may be partly influenced by age-dependent signals ‘leaking’ from the heart.
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback