Legendary Vegas handicapper Bruce Marshall has studied the trends and found the best betting values during the Week 6 college football schedule

Michigan State visits Oregon as we continue our college football odds series with a Michigan State-Oregon prediction and pick.

The Week 6 college football slate isn't loaded with big games, but two top-10 teams, Missouri and Michigan, are underdogs on the road.

Five Free Press sports writers make their picks as Michigan State football hosts Ohio State under the Spartan Stadium lights on Saturday.

SportsLine's model just revealed its college football picks for the Michigan State Spartans vs. Ohio State Buckeyes matchup on Saturday

Ohio State football is 4-0 after winning at Michigan State on Saturday, and the odds to extend that perfect start lean in the Buckeyes’ favor. OSU is a 21-point favorite, according to DraftKings, in its home game against Iowa on Saturday (3:30 p.

Ohio State was rolling along on their opening drive, until a 15-yard penalty drove the Buckeyes back outside the redzone and stalled the drive. Ohio State settled for three points, but the offense looked to not have much resistance from Michigan State.

Michigan State is attempting to avoid back-to-back losses and has new injury concerns. The Spartans (3-1, 1-0 Big Ten) host No. 3 Ohio State (3-0, 0-0) on Saturday (7:30 p.m., Peacock) and although starting receiver Jaron Glover will be available,