Autophagy pathway in astrocytes raises possibility of Alzheimer's ...
WEB3 days ago · Credit: Korea Institute of Science and Technology. A research team has uncovered a new mechanism involving astrocytes for treating Alzheimer's disease (AD) and proposed a novel therapeutic target ...
Optogenetic targeting of cortical astrocytes selectively improves …
WEB9 hours ago · Alzheimer’s disease (AD) is a complex neurodegenerative condition that primarily affects cognitive functions, initially presenting as short-term memory disturbances 1,2.As the disease advances ...
New Astrocyte Target for Alzheimer’s Therapy - Neuroscience News
WEB3 days ago · Featured Neurology Neuroscience. · September 30, 2024. Summary: Researchers have identified a novel therapeutic target for Alzheimer’s disease by focusing on astrocytes, non-neuronal brain cells involved in waste removal. They found that astrocytic autophagy clears amyloid-beta (Aβ) oligomers, toxic proteins in Alzheimer’s patients, and ...
Genetic Tweaks in Astrocytes Could Be Key to Alzheimer's …
WEB2 days ago · When astrocytes in the brains of mice were genetically modified to trigger their autophagy forms, damage to neurons caused by Alzheimer's-like symptoms reversed and cognitive functions and memory improved, the researchers discovered. Two key genes involved, called SQSTM1 and LC3B, produce a protein that helps eat up …
New insights into astrocytes offer hope for Alzheimer's treatment
WEB3 days ago · Dr. Ryu and Dr. Suhyun Kim (the first author) commented, " Our findings show that astrocytic autophagy restores neuronal damage and cognitive functions in the dementia brain. We hope this study ...
New brain cell cleaner: astrocytes raise possibility of Alzheimer’s ...
WEB4 days ago · A research team led by Dr. Hoon Ryu from the Korea Institute of Science and Technology (KIST, President Sang-Rok Oh) Brain Disease Research Group, in collaboration with Director Justin C. Lee of the Institute for Basic Science (IBS, President Do-Young Noh) and Professor Junghee Lee from Boston University Chobanian & Avedisian School of Medicine, has uncovered a new mechanism involving ...
Astrocytes study identifies a new therapeutic target for Alzheimer's ...
WEBSep 23, 2024 · The study found that damaged astrocytes in Alzheimer's disease have less energy production and generate more stress on the mitochondria. The work is published in the journal Molecular...
New brain cell cleaner: astrocytes raise poss | EurekAlert!
WEB4 days ago · News Release 30-Sep-2024. New brain cell cleaner: astrocytes raise possibility of Alzheimer’s disease treatment. Autophagy plasticity in astrocytes enhances the removal of dementia-causing ...
New research shows astrocytes are key to swaying the pendulum …
WEBMay 29, 2023 · Star-shaped brain cells called astrocytes are key to swaying the pendulum in Alzheimer's disease progression, shows new game-changing research published today in Nature Medicine.
Pathological phenotypes of astrocytes in Alzheimer’s disease
WEBJan 4, 2024 · Astrocyte contribution to dysfunction, risk and progression in neurodegenerative disorders. Revisiting the critical roles of reactive astrocytes in neurodegeneration. Severe reactive...
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